Statement of Purpose Examples
The post has been contributed by Aparna Sakhare and are different examples of Statement of Purpose by Students of different sub disciplines.
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Doctoral study is a significant milestone in the perpetual journey to education and the best exposure to this would be a worthy platform to prove the skills and knowledge that I have learnt. With due reverence to the department and the university, I pen down a ‘statement of purpose’. This statement is an endeavour to project my credentials as an aspiring researcher, my achievements as a biotechnology/biology graduate, my interest in this doctoral program and my ambitions.
I have always been a curious child, seeking reason and logic behind my observations of the world around me, and of the explanations put forth by others. I was drawn towards biology by my uncle who is a Doctor. He would regularly take me to observe surgeries in his hospital and explain various concepts to me. This subject has driven my curiosity, understanding it provides me a sense of fulfilment.
The dynamic nature of a living system fills me with wonder. It is astounding to see how open yet tightly controlled a biological system is, in order to maintain homeostasis. This is precisely why I would like to pursue a career in research, so that I can acquire new skills & knowledge and contribute to science.
My schooling and college education played a pivotal role in shaping my future. I had excellent facilities and faculty, which laid emphasis on fundamentals.
This fired my interest in academics and research and thus I have worked consistently towards this goal, with distinctions in my school exams and a Master’s Degree in Biotechnology from the Institute of Bioinformatics & Biotechnology, University of Pune, India. I am now looking forward to doing a Ph.D. and sense that the experiences in my life have been so far instrumental in getting me equipped to embark on this venture.
Firstly, the 5 Years’ Master’s program in Biotechnology has taught me to analyse various biological topics relevant to a problem systematically.
The comprehensive integrated 5-year program that I undertook taught me both theoretical and practical aspects of a variety of life science subjects such as molecular biology, cell biology, immunology microbiology, and genomics.
During this course I have pursued many projects, drawing upon the knowledge and skills that I acquired through classroom teaching as well as extensive practical training.
Among the projects that I undertook, the work I did on Drosophila to study the tissue-specific functions of a metabolic sensor in the regulation of metabolic homeostasis and organismal physiology has been the most fascinating.
This project was a part of my dissertation that I accomplished under the guidance of Dr.UllasKolthur, Dept. of Biological Sciences (DBS), Tata Institute of Fundamental Research (TIFR), Mumbai, India from January 2013 to May 2013. In this project, I established a functional diversification between the head and abdominal fat body in Drosophila melanogaster.
I also evaluated the role of dSir2 in the head fat body in the regulation of metabolic homeostasis in an insulin signalling dependent manner. I customarily used techniques such as cloning, transformation and PCR in this project. This project has facilitated me understand the critical link between metabolic homeostasis and aging and hence the relevance of nutrient sensing pathways to study the same.
Previous to this exertion, I was selected for the prestigious national level Summer Fellowship Program, conducted by The Indian Academy of Sciences, Bangalore, India, in the summer of 2011. As a result I had the good opportunity to work under the guidance of Prof. Nand Kishore, Department of Chemistry, an Indian Institute of Technology (IIT) Bombay, India.
In this project I worked on the biophysical aspects of drug protein interactions. It abetted me understand the thermodynamics involved in the binding of drugs to BSA & Lysozyme and the physical chemistry underlying these interactions.
I used DSC, ITC, Fluorescence spectroscopy, CD spectroscopy and UV-vis spectroscopy to determine the physico-chemical parameters and correlate them to the structural consequences of changing a system from the free to bound state. The ligands selected for this study were Naproxen, Folic acid and CMP (Cytidine monophosphate).
I furthermore worked on a project, of one year duration, wherein I explored the signal transduction mechanisms by which flavones isolated from corn silk induce cell death in cancer cell lines under the guidance of Dr. Ayesha Khan, DST Young Scientist, Research associate, IBB, and University of Pune.
The project was titled, “Mitochondria Mediated Apoptosis Induced by Flavonoids Isolated from Corn Hair”,formed a part of the compulsory project in the 3rd year coursework (July 2010-May 2011). It was during this project that I developed a liking towards cancer biology.
I had the wonderful opportunity to present this work at Annual Conference in Biotechnology, IBB, University of Pune, and 19th April 2011, organized by IBB, University of Puneand at the Project competition organized by Pune Inter College Consortium (PICC) in March 2011.
Two other enlightening projects that I undertook while at IBB were “Hepatoprotective activity of two plants belonging to the Amaranthus and the Portulacaceae family and the evaluation of effect of food processing on anticancer activity of some common vegetables.”
I also attended various conferences during my coursework at IBB. The Mini-Symposium on Cancer Informatics Analysis and Informatics of Microarray Data, Organized by NCCS (National Centre for Cell Science) and Department of Bioinformatics, University of Pune, on 14th September, 2012 aided me understand the strength of bioinformatics as a tool to study Cancer and other biologically relevant issues.
It helped me interact with various eminent scientists and doctors who were working in the field of genomics and transcriptomics. The discussion on their research works was very inspiring. The National Conference on Recent Trends in Biotechnology and Industry-Academia Interaction organized by IBB and Department of Microbiology, University of Pune, India on 8th -9th March 2010 was an enriching experience.
I was propitious to attend the 1st Science Conclave with Nobel Prize Winners organized by IIIT, Allahabad, India in December 2008. It was a boundless opportunity to meet the Nobel Laureates. I could perceive their passion for science and their work during the presentations and personal interaction sessions.
After completing my Master’s degree in May 2013, I decided to join the Biotechnology Industry to acquire a perspective on how biological research gets translated into drugs and therapeutics that are qualified for administration to patients. I was blessed enough to work as research intern in the bioassay group, R&D at Lupin Biotech Limited, Wakad, Pune, India from November 2013-April 2014.
Here I worked on cell proliferation and signal transduction assays to evaluate the potencies of certain bio similar drugs. Presently I am working as a Research Officer in the Dept. of Cell Biology, R&D, Quant immune Solutions Pvt Ltd, Navi Mumbai, India since June 2014. My work here involves Cell line maintenance and characterization; and the development of ELISA based techniques to perform PK-PD studies of certain drugs in clinical samples.
I also had the noble opportunity to study the affinity and kinetics of protein-protein interactions using surface Plasmon resonance. This has helped me understand the physiology of drug distribution and the various factors which play a critical role in aiding/inhibiting its action.
Apart from technical skills, I have always been an active student. The various extra-curricular activities offered by my college sharpened other essential skills in me. I was part of the organizing committee for my college cultural fest and for the Science Day Program held in the Pune University.
I have been a member of the Editorial Board of school magazines and I found this different experience really fascinating. I have also had the privilege of teaching underprivileged children as a member of the student teaching committee of the “JAGRUTI” program. Along with all this, I have learnt to speak four languages and can write in three of them. My other interests include travelling, painting, music, cooking and reading.
All throughout my undergraduate and graduate career, I have equipped myself with participation in various technical symposiums attended seminars and have done projects across a spectrum of fields.
I believe that an interdisciplinary learning that I have strived to acquire, has taught me to look for answers and overcome challenges. Having knowledge in various fields certainly makes that job easier, as we know which field can cater to what part of the solution. This approach has really helped me in working in collaborative research initiatives and I wish to be a part of similar initiatives in future.
Therefore, I am now ready to pursue a PhD to advance my career into basic and translational research. I am a keen and hard-working individual with a passion for cancer biology. I am certain that I will be able to cope with the rigors of an International curriculum with ease. My determination to succeed and do well will enable me to be among the better students of your college.
I highly value time and resources and as highlighted in my application, I have worked hard in the last six years to thoroughly train myself to pursue a career in research. The cutting edge research environment at XYZ UNIVERSITY with dedicated research teams and technological facilities will be highly suitable for advancing my career.
I will be greatly honoured if I am given the opportunity to pursue one in your University and shall strive to contribute to the field of biology and the organization.